Table 7.

Main series including major hepatectomies performed without portal triad clamping in the past 15 years

Authors	Year	Type of study	Number of patients (MH / RH)	Chronic liver disease (%)	Vascular controla	Intra-operative blood loss (ml)	Transfusion rate or blood unit per patient	Overall morbidity	Severe morbidity	Mortality
Malassagne et al.10	1998	Cohort	43 / 36	14%	r-SHVE or l-SHVE	Ns	35%	18.6%	11.6%	2%
Descottes et al.49	2003	Cohort	87 / 73	0%	r-Inflow	980	52%	26%	NS	4.6%
Scatton et al.51	2004	Cohort	50 / 26	12%	None or r-Inflow or l-Inflow	250	26%	16% (surgical) 20% (medical)	6%	0%
Moug et al.16	2007	Cohort	59 / 30	3%	r-SHVE or l-SHVE	450	0%	20%	1%	0%
Ercolani et al.31	2008	Cohort	393 / ns	27%	PTC or r-Inflow or l-Inflow or THVE	Ns	0.59 unit	23.4%	NS	2.1%
Fu et al.42	2011	Ran-domized control trial	108 / 52	60%	r-Inflow or l-Inflow vs. MPV vs. PTC	354	6.7%	20%	NS	0%
Li et al.50	2011	Cohort	60 / 60	0%	r-Inflow	595	0.42 unit	35%	8.4%	0%
Wong et al.45	2011	Cohort	124 / 124	31%	r-Inflow (or none) vs. PTC	450	10.3%	22.4%	NS	1.7%
Viganòet al.17	2011	Cohort	171 / 92	8%	r-SHVE or l-SHVE	450	14.3%	38.3%	NS	1.2%
Present series		Cohort	181 / 181	0%	r-SHVE	500	16.6% 0.45 unit	42%	12%	1.6%

Studies that focused exclusively on a hepatectomy in patients with cirrhosis have been excluded.

When data were available for distinct groups, only those from the group with major or a right hepatectomy without portal triad clamping have been presented.

^aTechniques of vascular control: PTC, total portal triad clamping (continuous or intermittent). r-Inflow/l-Inflow, clamping/division of the right/left portal vein and hepatic artery. r-SHVE/l-SHVE, clamping/division of the right/left portal vein and hepatic artery + clamping/division of the ipsi-lateral hepatic vein (selective hepatic vascular exclusion/devascularization). THVE, Total hepatic vascular exclusion without preservation of the caval flow. MPV, Clamping of the main portal vein.

MH, major hepatectomy; RH, right hepatectomy; NS, not specified.