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Lipopolysaccharide (LPS) and m-S100A9 induce cytokine and nitric oxide (NO) secretion in bone marrow-derived dendritic cells (BM-DC). The BM-DC were stimulated with or without 100 ng/ml LPS or 20 μg/ml m-S100A9 protein. Supernatants were collected after 48 hr and cytokine concentration (a) and NO (b) were determined. Data of three independent experiments made in duplicate were compiled and analysed using Student's t-test: *P < 0·05; ***P < 0·005.
