Table 1.
Effect of diabetes mellitus on infarct size
|
Species |
DM |
|
Index ischemia |
|
First author |
Journal |
|---|---|---|---|---|---|---|
| type | duration | min | type | |||
|
Infarct size enlargement | ||||||
| Dog |
2 |
75 d |
120 |
regional, vivo |
Forrat |
Cardiovasc Res 1993 |
| Rat (SD) |
1 |
8 d |
25 |
regional, vivo |
Marfella |
Diabetologia 2002 |
| Rat (SD) |
1 |
8 d |
25 |
regional, vivo |
Di Filippo |
Diabetes 2005 |
| Rat (SD) |
1 |
30 d |
30 |
global, vitro |
Thirunavukkarasu |
Free Radic Biol Med 2007 |
| Rat (Wistar) |
1 |
2 w |
30 |
regional, vivo |
Xiao |
J Pharmacol Exp Ther 2004 |
| Rat (Zucker obese) |
2 |
|
30 |
regional, vivo |
Jordan |
J Pharmacol Exp Ther 2003 |
| Rat (Zucker obese) |
2 |
(10-12 w old) |
30 |
regional, vivo |
Katakam |
Am J Physiol 2007 |
| Rat (Zucker diabetic fatty) |
2 |
(10-12 w old) |
30 |
regional, vivo |
Yue |
Diabetes 2005 |
| Rat (Zucker diabetic fatty) |
2 |
(12-16 w old) |
30 |
regional, vivo |
La Bonte |
Am J Physiol 2008 |
| Rat (OLETF) |
2 |
(25-30 w old) |
20 |
regional, vivo |
Miki |
Diabetes 2009 |
| Rat (OLETF) |
2 |
(25-30 w old) |
20 |
regional, vivo |
Hotta |
Circ Res 2010 |
| Mice |
1 |
8 d |
25 |
regional, vivo |
Marfella |
Diabetes 2004 |
| Mice |
1 |
4 w |
60 |
regional, vivo |
Liu |
Diabetes 2005 |
| Mice (ob/ob) |
2 |
(8-10 w old) |
30 |
regional, vivo |
Bouhidel |
Am J Physiol 2008 |
| Mice (ob/ob) |
2 |
(8-10 w old) |
30 |
regional, vivo |
Calvert |
Diabetes 2008 |
| Mice (ob/ob) |
2 |
(10-12 w old) |
30 |
regional, vivo |
Zhu |
J Cell Mol Med 2011 |
| Mice (KK-Ay) |
2 |
(6 w old) |
40 |
regional, vivo |
Honda |
J Mol Cell Cardiol 2008 |
|
Infarct size reduction | ||||||
| Rabbit (NZ) |
1 |
8 w |
30 |
regional, vivo |
Hadour |
J Mol Cell Cardiol 1998 |
| Rat (SD) |
1 |
2 w |
30 |
regional, vivo |
Ma |
N-S Arch Pharmacol 2006 |
| Rat (Wistar) |
2 |
11-12 m |
30, 45 |
regional, vivo |
Liu |
Circulation 1993 |
| Rat (Wistar) |
1 |
1 w |
30 |
regional, vivo |
Ravingerová |
Mol Cell Biochem 2003 |
| Rat (Wistar) |
1 |
4 w |
30 |
regional, vivo |
Xu |
Exp Mol Pathol 2004 |
| Rat (Wistar) |
1 |
6 w |
30 |
regional, vivo |
Galagudza |
Neurosci Behav Physiol 2007 |
| Rat (Wistar) |
2 |
10-12 w |
30 |
global, vitro |
Kravchuk |
Exp Diabetes Res 2011 |
| Rat (Wistar-Kyoto) |
2 |
9 m |
40 |
regional, vitro |
Mozaffari |
Hypertension 2003 |
| Rat (Zucker diabetic fatty) |
2 |
(16 w old) |
50 |
regional, vitro |
Kristiansen |
Diabetologia 2004 |
| Rat (Goto-Kakizaki) |
2 |
(16 w old) |
50 |
regional, vitro |
Kristiansen |
Diabetologia 2004 |
| Rat (Goto-Kakizaki) |
2 |
(16 w old) |
45 |
regional, vitro |
Kristiansen |
Diabetologia 2011 |
|
No change in infarct size | ||||||
| Dog |
1 |
3 w |
60 |
regional, vivo |
Kersten |
Am J Physiol 2000 |
| Dog |
1 |
3 w |
60 |
regional, vivo |
Kersten |
Am J Physiol 2001 |
| Rabbit (NZ) |
1 |
10-16 w |
30 |
regional, vivo |
Vogel |
Circ Res 1988 |
| Rabbit (NZ) |
1 |
4-5 w |
60 |
regional, vivo |
Nieszner |
Exp Clin Endocrinol Diabetes 2002 |
| Rabbit (NZ white) |
1 |
5-6 w |
30 |
regional, vivo |
Ebel |
Pflügers Arch 2003 |
| Rat (SD) |
1 |
6 w |
30 |
regional, vivo |
Ma |
N-S Arch Pharmacol 2006 |
| Rat (SD) |
1 |
2 w |
30 |
regional, vivo |
Gross |
Diabetes 2007 |
| Rat (SD) |
1 |
4 w, 8 w |
30 |
global, vitro |
Shi-Ting |
Biomed Pharmacother 2010 |
| Rat (SD) |
1 |
4-5 w |
30 |
regional, vivo |
Drenger |
Anesthesiology 2011 |
| Rat (SD) |
1 |
4 w |
30 |
global, vitro |
Okazaki |
J Mol Cell Cardiol 2011 |
| Rat (Wistar) |
1 |
8 w |
30 |
regional, vitro |
Joyeux |
Cardiovasc Res 1999 |
| Rat (Wistar) |
1 |
8 w |
30 |
regional, vivo |
Ravingerová |
Mol Cell Biochem 2003 |
| Rat (Wistar) |
1 |
20 w |
30 |
regional, vivo |
Xu |
Exp Mol Pathol 2004 |
| Rat (Wistar) |
1 |
4 w |
25 |
global, vitro |
Ghaboura |
Basic Res Cardiol 2011 |
| Rat (Goto-Kakizaki) |
2 |
|
35 |
regional, vitro |
Tsang |
Diabetes 2005 |
| Rat (Goto-Kakizaki) |
2 |
|
35 |
regional, vitro |
Bhamra |
Basic Res Cardiol 2008 |
| Rat (Goto-Kakizaki) |
2 |
(12 w old) |
35 |
regional, vivo |
Bulhak |
Am J Physiol 2009 |
| Rat (Goto-Kakizaki) |
2 |
|
30 |
regional, vivo |
Matsumoto |
Cardiovasc Drug Ther 2009 |
| Mice |
1 |
2 w |
30 |
global, vitro |
Przyklenk |
Antioxid Redox Signal 2011 |
| Mice (ob/ob) | 2 | (12-14 w old) | 30 | global, vitro | Przyklenk | Antioxid Redox Signal 2011 |
SD, Sprague–Dawley; NZ, New Zealand; OLETF, Otsuka Long-Evans-Tokushima fatty; d, days; w, weeks.