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Thermodynamic parameters for binding of KRIT1 FERM domain to HEG1 cytoplasmic tail
| Clone | n | Kd | ΔH° | ΔG° | TΔS° |
| µM | Kcal/mol | Kcal/mol | Kcal/mol | ||
| Wild-type | 1.01 | 1.2 ± 0.14 | −10.0 | −8.1 | −1.9 |
Kd = 1 / Ka . ΔG° = −RTlnKa. ΔG = ΔH − TΔS. Ka, association constant; ΔH, enthalpy changes; ΔG, Gibbs energy changes; R, gas constant; T, absolute temperature; ΔS, entropy changes.
