Table 4.

Intraclass correlation coefficients and corresponding 95% confidence intervals for regional [¹¹C]AF150(S) brain uptake (%ID/g).

Number of subjects (n = 10)
ROI	Observer 1 versus 2				Observer 1 versus 3
	ICCA	95% CL	ICCC	95% CL	ICCA	95% CL	ICCC	95% CL
Left striatum	0.998	(0.991, 0.999)	0.997	(0.990, 0.999)	0.997	(0.988, 0.999)	0.997	(0.988, 0.999)
Right striatum	0.995	(0.978, 0.999)	0.995	(0.981, 0.999)	0.998	(0.991, 0.999)	0.998	(0.992, 0.999)
Hippocampus	0.997	(0.989, 0.999)	0.997	(0.989, 0.999)	0.992	(0.769, 0.999)	0.997	(0.989, 0.999)
Frontal cortex	0.930	(0.491, 0.985)	0.961	(0.853, 0.990)	0.985	(0.886, 0.997)	0.991	(0.963, 0.998)
Posterior cortex	0.956	(0.826, 0.989)	0.962	(0.856, 0.990)	0.927	(0.102, 0.987)	0.978	(0.913, 0.994)
Medulla oblongata	0.966	(0.879, 0.991)	0.967	(0.873, 0.992)	0.904	(−0.022, 0.984)	0.985	(0.940, 0.996)
Cerebellum	0.993	(0.972, 0.998)	0.992	(0.969, 0.998)	0.970	(0.499, 0.994)	0.988	(0.954, 0.999)
	Observer 2 versus 3				Overall
Left striatum	0.997	(0.988, 0.999)	0.997	(0.989, 0.999)	0.997	(0.992, 0.999)	0.997	(0.992, 0.999)
Right striatum	0.998	(0.991, 0.999)	0.997	(0.990, 0.999)	0.997	(0.990, 0.999)	0.997	(0.991, 0.999)
Hippocampus	0.987	(0.632, 0.998)	0.996	(0.983, 0.999)	0.992	(0.947, 0.998)	0.997	(0.991, 0.999)
Frontal cortex	0.907	(0.080, 0.983)	0.968	(0.878, 0.992)	0.937	(0.682, 0.985)	0.972	(0.922, 0.992)
Posterior cortex	0.856	(0.062, 0.971)	0.939	(0.776, 0.985)	0.911	(0.605, 0.979)	0.959	(0.885, 0.989)
Medulla oblongata	0.895	(0.306, 0.977)	0.945	(0.794, 0.986)	0.919	(0.608, 0.981)	0.966	(0.904, 0.991)
Cerebellum	0.957	(0.663, 0.991)	0.977	(0.910, 0.994)	0.974	(0.881, 0.994)	0.986	(0.960, 0.996)

Level of agreement: ≤0.40 poor to fair, 0.41–0.60 moderate, 0.61–0.80 substantial, 0.81–1.00 almost perfect.