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SFN upregulated renal expression of Nrf2 and its downstream genes at mRNA level. Nrf2 (a) and its downstream genes, NQO1 (b), HO-1 (c), SOD1 (d), SOD2 (e), and CAT (f) expression at mRNA level were detected by RT-PCR. Data were presented as means ± SD (n = 6 at least). (*P < 0.05 versus control; # P < 0.05 versus DM group).
