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Figure 1. Growth-inhibitory effect of VE 465 on ovarian cancer cell lines as detected by MTT proliferative assay. (A) VE 465 on cell lines 2774, A2780, 2008/C13, Hey, NMP1, OVCAR3, and SKOV3. (B) IC50 of VE 465 in different ovarian cancer cell lines after treatment for 96 h. The experiments were repeated three times. (C) Western blot analysis of the expression of Aurora kinases A and B, p53, and ER-α in ovarian cancer cell lines.
