Table 3. Pretreatment prediction of tumor significance.
Pretreatment Criterion* | No. Tumor Category |
% Pos. Predictive Value | % Neg. Predictive Value | |||
---|---|---|---|---|---|---|
Insignificant | Minimal | Moderate | Advanced | |||
Transrectal ultrasound: | ||||||
Neg. | 16 | 8 | 39 | 10 | 83 | 22 |
Pos. | 10 | 5 | 31 | 12 | ||
Ca size (mm.VGleason pattern 4 or 5: Less than 3 on 1 core/none |
15 | 7 | 28 | 4 | 87 | 28 |
3 or More on any core/any | 25 | 22 | 96 | 43 | ||
PSA density/pathological findings on needle biopsy Less than 0.15/good |
5 | 1 | 2 | 0 | 84 | 63 |
0.15 or More/poor | 10 | 6 | 34 | 14 |
Positive—suspicious lesion. Negative—no suspicious lesion. Good pathological findings refer to a Gleason score of less than 7, fewer than 3 cores involved with cancer and less than 50% involvement of any core with cancer. Poor pathological findings refer to a Gleason score of 7 or more, 3 or more cores involved with cancer, or 50% or more involvement of any core with cancer.