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Capsaicin evokes significant CGRP release from human dental pulp. Capsaicin (1 – 30 μM; closed bars) induces CGRP release in a concentration-dependent manner from human dental pulp compared to vehicle (open bars) as expressed by amount fmol released per pulp (A). The same data is expressed as percentage of basal release (B). * indicates significance at p<0.05 compared to vehicle; n=15–18 teeth per group.
