Table 1.
Comparison of dissociation constant (KD) values determined in this study with those reported in the literature
| Interaction | KD[a] | KD [b] Reported |
|---|---|---|
| Avidin – Biotin | 3 fM | 1 fM [15] |
| Protein G – IgG | 0.4 pM | 50 pM [16] |
| Concanavalin A – Dextran | 11.8 nM | 90 nM [18] |
| Folate receptor – Folic Acid | 16 nM | 0.1 nM [26] |
| Folate receptor – anti-FR Ab | 0.19 nm | 2.2 nM [22] |
| EpCAM receptor – anti-EpCAM Ab | 73 pM | 550 pM [23] |
| TTC – Doxorubicin | 4.1 μM | 9.4 μM [29] |
| TTC – Rhein | 33.6 μM | N/A |
| CTB – Dextran | 4.9 μM | 14 mM [28] |
| CTB – Glucose | 36 μM | N/A |
| CTB – Galactose | 3.5 μM | N/A |
| CTB – Lactose | 88 μM | N/A |
| CTB – β-Cyclodextrin | 3.6 μM | N/A |
[a]
Values determined using bMR nanosensor competition assay
[b]
Values reported in the literature, corresponding refence in bracket