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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Birth Defects Res B Dev Reprod Toxicol. 2011 Oct;92(5):404–412. doi: 10.1002/bdrb.20326

Fig. 2.

Fig. 2

The postnatal survival of pups is shown as the percent of the litter alive on PND1 to 10, 14, 17, and 22 for WT (A) and PPARa KO (B) strains. A significant decrease (p < 0.001) compared to control occurred only in the WT litters of dams exposed to 0.6 or 1 mg/kg on GD1 to 17. Data shown are the mean of litter means for 10, 9, 6, 7, and 10 WT and 7, 11, 9, 8, and 16 KO litters, in the order listed in the legends, respectively.

(Reproduced with permission from Abbott BD, et al. 2007. Perfluorooctanoic acid-induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator-activated receptor-alpha. Toxicol Sci 98:571–581.)