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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Am J Transplant. 2008 Jul 28;8(9):1829–1839. doi: 10.1111/j.1600-6143.2008.02337.x

Figure 6. Anti-non-gal xenoantibodies bind to a carbohydrate xenoantigen that is structurally similar to the gal carbohydrate.

Figure 6

GalTKO cells that are genetically modified to express the gal carbohydrate after transduction with viral vectors expressing the gene encoding porcine α 1,3 galactosyltransferase show higher levels of binding of anti-non-gal xenoantibodies when compared with non-tranduced GalTKO cells. Positive binding was evaluated by mean channel shift. PEGKO42 cells are GalTKO pig endothelial cells. Data shown is representative of three independent transductions +/− standard deviation.