Table 3.

Changes in haemoglobin level, white blood cell and CD4 count during treatment among pulmonary tuberculosis patients with (n = 197) or without (n = 1008) diabetes

	Patients without diabetes	Patients with diabetes
	(n = 2008)	(n = 197)
	Mean (95% CI)	Mean (95% CI)	P
Haemoglobin, g pr. dL
Baseline	10.8 (10.6; 10.9)	10.7 (10.4; 11.0)
2 months	12.3 (12.2; 12.5)	11.7 (11.4; 12.0)
Increase	1.6 (1.4; 1.7)	1.0 (0.7; 1.3)
Difference	0.6 (0.3; 0.9)		< 0.001
5 months	13.0 (12.8; 13.1)	12.4 (12.1; 12.7)
Increase	2.2 (2.1; 2.3)	1.7 (1.4; 2.0)
Difference	0.5 (0.2; 0.9)		0.004
White blood cell count (total), 109 cells pr. L
Baseline	6.4 (6.3; 6.6)	6.8 (6.5; 7.1)
2 months	4.7 (4.6; 4.8)	5.0 (4.7; 5.3)
Increase	−1.7 (−1.9; -1.6)	−1.7 (−2.1; -1.4)
Difference	0.02 (−0.3; 0.4)		0.918
5 months	4.3 (4.1; 4.4)	4.6 (4.3; 4.9)
Increase	−2.2 (−2.3; -2.0)	−2.2 (−2.5; -1.8)
Difference	−0.03 (−0.4; 0.3)		0.889
Neutrophil granulocytes, 109 cells pr. L
Baseline	4.1 (4.0; 4.2)	4.6 (4.4; 4.8)
2 months	2.3 (2.2; 2.4)	2.6 (2.4; 2.8)
Increase	−1.8 (−2.0; -1.7)	−2.0 (−2.2; -1.7)
Difference	0.1 (−0.2; 0.4)		0.493
5 months	1.8 (1.7; 2.0)	2.2 (2.0; 2.5)
Increase	−2.3 (−2.4; -2.1)	−2.3 (−2.6; -2.1)
Difference	0.1 (−0.2; 0.4)		0.658
CD4 count, cells pr. μL
Baseline	425.9 (408.9; 442.8)	409.2 (370.6; 447.8)
2 months	477.5 (459.9; 495.2)	435.1 (393.7; 476.5)
Increase	51.7 (29.7; 73.6)	25.9 (−25.0; 76.8)
Difference	25.7 (−29.7; 81.2)		0.362
5 months	436.2 (417.7; 454.6)	396.6 (353.7; 439.6)
Increase	10.3 (−12.3; 32.9)	−12.5 (−64.6; 39.6)
Difference	22.8 (−33.9; 79.6)		0.431

Data are mean (95% confidence interval) based on a linear mixed-effects model, adjusted for age, sex, HIV status, alpha-1 glycoprotein, smoking habits, alcohol intake, and nutritional intervention.