Table 1.
Patient characteristics
| Variable |
METAVIR F0-3 |
METAVIR F4 |
Pvalue |
|---|---|---|---|
| n = 109 | n = 18 | ||
| Age, year |
51.6(1.2) |
62.7(1.5) |
<.001 |
| Gender (n) |
|
|
1.000 |
| Male |
51 |
8 |
|
| Female |
58 |
10 |
|
| BMI, kg/m2 |
24.64(0.33) |
24.02(0.79) |
.477 |
| HCV genotype (n) |
|
|
1.000 |
| 1 |
53 |
9 |
|
| Non-1 |
56 |
9 |
|
| HCV RNA, x 106, copies/mL |
8.16(1.21) |
1.02(0.52) |
<.001 |
| ALT, IU/L |
97.94(8.24) |
64.28(8.07) |
.005 |
| ALT/ULN (n) |
|
|
.273 |
| <1x |
26 |
5 |
|
| ≧1x <2x |
35 |
7 |
|
| ≧2x <3x |
21 |
5 |
|
| ≧3x <4x |
7 |
1 |
|
| ≧4x |
20 |
0 |
|
| ActiTest, A score |
0.51(0.03) |
0.51(0.06) |
.928 |
| Bilirubin, umol/L |
16.80(0.54) |
22.36(2.00) |
<.001 |
| Cr, umol/L |
71.80(4.34) |
65.42(4.35) |
.301 |
| INR |
1.02(0.01) |
1.12(0.03) |
<.001 |
| Na, meq/L |
137.90(0.24) |
137.83(0.60) |
.918 |
| Platelet, x 109/L |
176.61(5.67) |
121.44(9.73) |
<.001 |
| Child-Pugh grade (n) |
|
|
|
| A |
|
16 |
|
| B |
|
2 |
|
| C |
|
|
|
| METAVIR F (n) |
|
|
|
| F0 |
0 |
|
|
| F1 |
46 |
|
|
| F2 |
40 |
|
|
| F3 |
23 |
|
|
| F4 |
|
18 |
|
| METAVIR A (n) |
|
|
.484 |
| A0 |
31 |
3 |
|
| A1 |
60 |
10 |
|
| A2 |
16 |
5 |
|
| A3 |
2 |
0 |
|
| Hepatic steatosis (n) |
|
|
1.000 |
| S0 |
15 |
2 |
|
| S1 |
37 |
6 |
|
| S2 |
52 |
10 |
|
| S3 |
4 |
0 |
|
| S4 |
1 |
0 |
|
| Liver SWV, m/s |
1.65(0.06) |
2.62(0.19) |
<.001 |
| FibroTest, F score | 0.57(0.03) | 0.79(0.04) | <.001 |
Continuous variables were presented as mean (standard error) and examined using the Student’s t test. Categorical variables were estimated using Fisher’s exact test. ALT, serum alanine aminotransferase; Cr, serum creatinine; INR, international normalized ratio of prothrombin time; METAVIR A, activity; METAVIR F, fibrosis; Na, serum sodium; SWV, shear wave velocity.