Table 3.
Characteristics of patients with community-acquired pneumonia according to etiologic categories (N° = 390)
| Characteristics | Conventional Bacteria (N = 163 ) | Atypical Agent (N = 151) | Virus (N = 41) | Mixed Infection (N = 35) | P value† |
|---|---|---|---|---|---|
| Age, years, mean (SD) |
68.9 (18.3) |
47.5 (18.3) |
66.1 (17.5) |
61.9 (22.9) |
<0.0001 |
| Female |
72 (44.2) |
51 (36.8) |
19 (46.3) |
9 (25.7) |
0.07 |
| Immunized against influenza |
83 (53.6) |
32 (22.2) |
32 (82.1) |
19 (54.3) |
<0.0001 |
| Immunized against pneumococcal infection |
10 (6.8) |
4 (2.8) |
2 (5.1) |
1 (2.9) |
0.4 |
| Number of comorbid conditions |
|
|
|
|
0.002 |
| 0 |
96 (60) |
120 (81.6) |
24 (60) |
21 (60) |
|
| 1 |
44 (27.5) |
20 (13.6) |
13 (32.5) |
11 (31.4) |
|
| >1 |
20 (12.5) |
7 (4.8) |
3 (7.5) |
3 (8.6) |
|
| Underlying diseases |
|
|
|
|
|
| Neoplastic disease |
10 (6.1) |
4 (2.7) |
0 (0) |
3 (8.6) |
0.2 |
| Liver disease |
1 (0.6) |
2 (1.3) |
0 (0) |
3 (8.6) |
0.005 |
| Congestive heart failure |
8 (4.9) |
4 (2.7) |
0 (0) |
0 (0) |
0.2 |
| Cerebrovascular disease |
11 (6.8) |
2 (1.3) |
1 (2.4) |
2 (5.7) |
0.09 |
| Renal disease |
7 (4.3) |
4 (2.7) |
1 (2.4) |
2 (5.7) |
0.7 |
| Chronic obstructive pulmonary disease |
34 (21.1) |
9 (6.1) |
11 (27.5) |
4 (11.4) |
0.0003 |
| Diabetes mellitus |
18 (11.3) |
13 (8.8) |
6 (14.6) |
3 (8.6) |
0.7 |
| Severity of illness at diagnostic |
|
|
|
|
|
| CURB-65 score* |
|
|
|
|
<0.0001 |
| 0-1 |
79 (48.5) |
131 (86.8) |
29 (70.7) |
20 (57.1) |
|
| 2 |
47 (28.8) |
13 (8.6) |
9 (22) |
10 (28.6) |
|
| >2 |
37 (22.7) |
7 (4.6) |
3 (7.3) |
5 (14.3) |
|
| Bilateral or multilobe radiographic involvement | 38 (23.5) | 7 (4.7) | 0 (0) | 2 (5.7) | <0.0001 |
SD = standard deviation.
Data are presented as numbers (percentage) of patients unless otherwise stated. Percentages exclude patients with missing data.
* Severity of illness on admission assessed with CURB-65 score (Confusion, Urea nitrogen, Respiratory rate, Blood pressure, age ≥65 year).
† The p-value obtained from the Chi-square or Fisher exact test for categorical variables, and Kruskal-Wallis test for continuous variables.