Table 1. Inhibitory potencies of sialoside analogues (1-9) against murine Sn.a.
Compound | R = | IC50 (μM) |
---|---|---|
1 | 4.82 ±0.14 | |
2 | 0.38 ±0.04 | |
3 | 7.25 ±0.61 | |
4 | 21.6 ±2.1 | |
5 | 25.8 ±1.4 | |
6 | >200 | |
7 | >400 | |
8 | 26.5 ±3.8 | |
9 | >500 |
All titrations were performed in triplicate, and standard deviation is given from three independent measurements.