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. Author manuscript; available in PMC: 2013 Sep 26.
Published in final edited form as: J Am Chem Soc. 2012 Sep 14;134(38):15696–15699. doi: 10.1021/ja307501e

Table 1. Inhibitory potencies of sialoside analogues (1-9) against murine Sn.a.

graphic file with name nihms-408419-t0006.jpg

Compound R = IC50 (μM)
1 graphic file with name nihms-408419-t0007.jpg 4.82 ±0.14
2 graphic file with name nihms-408419-t0008.jpg 0.38 ±0.04
3 graphic file with name nihms-408419-t0009.jpg 7.25 ±0.61
4 graphic file with name nihms-408419-t0010.jpg 21.6 ±2.1
5 graphic file with name nihms-408419-t0011.jpg 25.8 ±1.4
6 graphic file with name nihms-408419-t0012.jpg >200
7 graphic file with name nihms-408419-t0013.jpg >400
8 graphic file with name nihms-408419-t0014.jpg 26.5 ±3.8
9 graphic file with name nihms-408419-t0015.jpg >500
a

All titrations were performed in triplicate, and standard deviation is given from three independent measurements.