Figure 4. Binding titration curve of Fl-C35 and its binding stability to the 5HB.
(A) The fluorescence polarization response of Fl-C35 binding to the 5HB was monitored as the concentration of the 5HB increased. The experiment was performed using 5 nM Fl-C35 and the 5HB concentration ranged from 0 to 500 nM. (B) The stability of FL-C35 binding to the 5HB was monitored over a 24 hr period using 5 nM of Fl-C35 in the presence of increasing amount of the 5HB.