Figure 3. Intramyocardial lipid accumulation in mice.

Myocardial triacylglyceride levels (A) in db/db mice and MHC-PPARα mice with or without APS administration at 20 week-old were determined by ESI/MS. Mean levels of TAG-associated fatty acid with chain length of 16∶0 (B), 18∶0 (C), 18∶1 (D), and 18∶2 (E) in the hearts of each group were shown respectively. (F) representative images of myocardium stained with oil red O. All groups n = 8. Bars represent means±S.E.M. *P<0.05 vs. C57 mice, # P<0.05 vs. untreated db/db mice, † P<0.05 vs. untreated MHC-PPARα mice.