Table 3. Characteristics of treatment-naïve HIV-infected adults: comparison of HBsAg+veHBV DNA+ve versus HBsAg-ve HBV DNA+ve individualsa.
| Characteristic | HBV DNA+ve participants (n = 71) | HBsAg+veHBV DNA+ve (n = 26) | HBsAg-ve HBV DNA+ve (n = 45) | Significance–p valuesb | |||||||||
| All | Male[A] | Female[A] | All[D] | Male[B] | Female[B] | All[D] | Male[C] | Female[C] | A | B | C | D | |
| Numbers (%) | 71 | 30(42%) | 41(58%) | 26 | 13(50%) | 13(50%) | 45 | 17(38%) | 28(62%) | n/a | 0.42 | 0.54 | n/a |
| Age in years | 35(28–41) | 37(34–47) | 31(25–39) | 34(27–28) | 35(33–39) | 29(25–35) | 36(29–45) | 38 (35–47) | 34(28–40) | 0.01 | 0.07 | 0.035 | 0.14 |
| Age at sexual debut in years c | 17(16–18) | 17(16–19) | 16(15–18) | 17(16–20) | 18(16–22) | 17(15–18) | 16(15–18) | 17(16–18) | 16(15–18) | 0.12 | 0.11 | 0.66 | 0.23 |
| Lifetime sexual partners d | 3(2–5) | 4(2–8) | 3(2–5) | 3(1–6) | 2(1–6) | 3(1–5) | 4(2–5) | 4(2–10) | 3(2–5) | 0.34 | 0.98 | 0.17 | 0.38 |
| BMI in kg m−2 | 22(20–24) | 21(20–23) | 22(20–25) | 23(20–25) | 22(20–23) | 25(20–27) | 21(20–23) | 21(20–22) | 22(20–24) | 0.37 | 0.29 | 0.64 | 0.30 |
| ALT in U L−1 | 23(15–37) | 31(18–59) | 20(12–28) | 30(19–59) | 35(22–60) | 21(12–39) | 20(13–32) | 27(15–37) | 19(13–25) | 0.027 | 0.29 | 0.12 | 0.07 |
| Apoptosense U L−1 | 114(91–158) | 117(91–160) | 114(91–152) | 113(84–156) | 110(75–150) | 114(91–161) | 114(94–158) | 121(96–188) | 114(91–142) | 0.96 | 0.27 | 0.37 | 0.62 |
| CD4 cells mm−3 | 148(74–199) | 104(60–171) | 180(103–245) | 152 (101–202) | 125 (98–184) | 179 (132–255) | 147(68–196) | 87(57–165) | 181(91–229) | 0.006 | 0.13 | 0.016 | 0.52 |
| LogHBVVL e | 3.72(3.04–4.41) | 3.76(2.95–4.47) | 3.61(3.08–4.35) | 3.64(2.73–4.80) | 4.14(2.74–5.44) | 3.22(2.54–4.01) | 3.78(3.15–4.35) | 3.74(2.99–4.28) | 3.81(3.19–4.44) | 0.66 | 0.14 | 0.59 | 0.74 |
a
all values expressed as “Median (Interquartile Range)”.
b
comparing the columns marked by UPPER case letter; statistical significance is indicated by underlining.
c
9 samples without data points omitted.
d
2 samples without data points omitted.
e
“LogHBVVL” indicates the log of the HBV viral load rounded to two decimal places [A Mann-Whitney U test was used on the untransformed viral loads (IU ml−1)].