Comparison of material properties of (A) Green strain at failure, (B) ultimate tensile stress (UTS), (C) tangent modulus, and (D) transition strain between collagen and fibrin networks under different digestion conditions. In general, collagen and fibrin networks obtained from co-gel digestion exhibited similar UTS, but higher failure strains and lower tangent modulus when compared to their pure counterparts. Material properties of the undigested co-gel (CG in PBS) cannot be derived from the sum of properties of the digested co-gels (CG in Pn, CG in Cs), showing the the rule of mixtures does of apply to these collagen-fibrin systems. Error bars represent 95% confidence intervals, n ≥ 6 for all samples. * and # represent statistical significance at the 95% and 90% levels respectively.