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Activities of caspase-8 and caspase-3 in MDA-MB-435 cells serially imaged using C8/C3/PULSin. The cells were incubated with C8/C3/PULSin for 4 hr and treated with TRAIL (100 ng/mL). Images were collected at 30 min intervals over 4 hr. Green (FPG456), caspase-8; red (Cy5.5), caspase-3.
