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. Author manuscript; available in PMC: 2013 Oct 10.
Published in final edited form as: J Control Release. 2012 Jun 23;163(1):18–24. doi: 10.1016/j.jconrel.2012.06.021

Figure 5.

Figure 5

Skin distribution of PTX delivered via TyroSpheres (0% HPMC) and gel-like TyroSpheres (1% HPMC).

LC-MS was used as a detection method to quantify PTX deposited into different skin strata and receptor fluid. On the Y-axis, the units of PTX permeation (#) are: (ng/cm2) of tissue surface area for PTX in the epidermis and dermis, and (ng/mL) for PTX measured in the receptor compartment. The statistical data is expressed as mean ±SE (n = 8); p < 0.001 (*) was considered to be statistically significant between the amount of PTX present in the epidermis and dermis for both TyroSpheres and gel-like TyroSpheres.