Table 3.

AECK-DD concentration in 24-h collected urine samples of nineteen healthy human subjects measured by GC-MS/MS^a

No	Gender	Age (years)	AECK-DD (nM)	Creatinine (mM)	AECK-DD/Creatinine (nmol/mmol)
1	Male	29	45.7	11.5	3.97
2	Female	40	<LOQb	7.1	<LOQb
3	Female	28	14.4	6.6	2.18
4	Male	26	21.0	13.0	1.62
5	Male	60	3.73	18.5	0.20
6	Female	47	12.7	2.3	5.52
7	Female	40	3.31	8.1	0.41
8	Male	47	4.76	12.0	0.40
9	Male	42	9.65	2.97	3.25
10	Male	50	2.85	7.69	0.37
11	Male	34	19.1	3.22	5.93
12	Male	47	6.4	14.4	0.44
13	Male	41	22.9	5.93	3.86
14	Male	30	2.2	21.2	0.10
15	Male	42	14.9	12.4	1.20
16	Male	26	3.12	10.5	0.30
17	Male	47	5.1	22.5	0.23
18	Female	56	<LOQ b	6.02	<LOQ b
19	Male	52	6.1	21.5	0.28
Mean ± SD		41.3 ± 10.2	10.5 ± 11.1	10.9 ± 6.4	1.6 ± 2.0

^aSRM of m/z 328 to m/z 268 for AECK-DD and m/z 330 to m/z 270 for ¹³C₂-AECK-DD (IS added to a final concentration of 250 nM)

^bLOQ is about 2 nM.