Table 3.

Comparison of Classification System Modeling and Estimates for Classification Systems using Model Averaging for the Disease Relapse, Treatment Resistance, ESKD, Death

System Modeling for Disease Relapse				Model Averaging:
Classification System	Classification Category	Δ AICc per system model	Model Weight	Model Rank	P values	Hazard Ratio	Low (95%CI)	High (95%CI)
PR3/MPO		0.000	0.989	1
	MPO					Reference
	PR3				0.0004	1.888	1.328	2.686
CHCC		11.651	0.003	3
	Microscopic polyangiitis					Reference
	Kidney Limited Disease				0.978	0.999	0.961	1.034
	Granulomatosis with polyangiitis				0.963	1.001	0.962	1.042
EMA		9.516	0.003	2
	Microscopic polyangiitis					Reference
	Granulomatosis with polyangiitis				0.935	0.995	0.879	1.126
System Modeling for Treatment Resistance				Model Averaging
Classification System	Classification Category	Δ AICc per system model	Weight(model or variables)	Model Rank	P value	OR	Low (95%CI)	High (95%CI)
PR3/MPO		1.93	0.256	2
	MPO					Reference
	PR3				0.744	0.952	0.709	1.278
CHCC		4.47	0.072	3
	Microscopic Polyangiitis					Reference
	Kidney Limited Disease				0.966	0.997	0.850	1.168
					0.961	1.004	0.841	1.120
EMA		0	0.672	1
	Microscopic Polyangiitis
	Granulomatosis with Polyangiitis				0.257	1.312	0.817	2.132
System Modeling for ESKD				Model Averaging
Classification System	Classification Category	Δ AICc per system model	Weight(model or variables)	Model Rank	P value	HR	Low (95%CI)	High (95%CI)
PR3/MPO		2.849	0.154	3
	MPO					Reference
	PR3				0.907	1.009	0.871	1.168
CHCC		0	0.641	1
	Microscopic Polyangiitis					Reference
	Kidney Limited Disease				0.186	1.302	0.880	1.926
	Granulomatosis with Polyangiitis				0.693	0.923	0.619	1.375
EMA		2.288	0.204	2
	Microscopic Polyangiitis					Reference
	Granulomatosis with Polyangiitis				0.759	1.029	0.855	1.239
System Modeling for Death				Model Averaging
Classification System	Classification Category	Δ AICc per system model	Weight(model or variables)	Model Rank	P value	HR	Low (95%CI)	High (95%CI)
PR3/MPO		0	0.495	1
	MPO					Reference
	PR3				0.417	1.141	0.830	1.568
CHCC		3.952	0.069	3
	Microscopic Polyangiitis					Reference
	Kidney Limited Disease				0.987	1.001	0.900	1.113
	Granulomatosis with Polyangiitis				0.951	0.996	0.863	1.149
EMA		0.251	0.437	2
	Microscopic Polyangiitis					Reference
	Granulomatosis with Polyangiitis				0.488	1.113	0.822	1.508