Table 4.

Multivariable Hazard Ratios for Time to Relapse by CHCC Disease Categories for MPO- and PR3- ANCA Specificity

ANCA specificity and Disease Definition Categories (n)	Hazard Ratio (95% CI)*	P-value
MPO-ANCA, KLD (56)	Reference 1.0	NA
MPO-ANCA, MPA (121)	1.56 (0.70, 3.48)	0.276
MPO-ANCA, GPA (21)	1.36 (0.47, 3.90)	0.568
PR3-ANCA, KLD (20)	2.49 (0.89, 6.95)	0.081
PR3-ANCA, MPA (79)	2.45 (1.07, 5.63)	0.035
PR3-ANCA, GPA (77)	3.15 (1.34, 7.40)	0.009

^*The proportional hazards model for these results controlled for disease involvement of the lung and upper airways.

MPA = Microscopic Polyangiitis, GPA = Granulomatosis with Polyangiitis, KLD=Kidney Limited Disease