Table 2.
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|
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PAX8/PPARG detection in the FNA samples |
PAX8/PPARG detection in the FFPE samples |
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Sample ID | Histology | Cytology | PAX8 (exon 8)/PPARG | PAX8 (exon 9)/PPARG | PAX8 (exon 10)/PPARG | PAX8 (exon 8)/PPARG | PAX8 (exon 9)/PPARG | PAX8 (exon 10)/PPARG |
23 | FTC | Indeterminate | Positive | Negative | Negative | Negative | Negative | Negative |
132 | FTC | Indeterminate | Positive | Negative | Negative | Negative | Negative | Negative |
133 | FTC | Indeterminate | Positive | Negative | Negative | Negative | Negative | Negative |
161 | FTC | Indeterminate | Positive | Negative | Negative | Positive | Negative | Negative |
29 | FA | Indeterminate | Negative | Negative | Negative | Negative | Negative | Positive |
50 | FA | Indeterminate | Positive | Positive | Positive | Positive | Positive | Positive |
81 | FA | Indeterminate | Negative | Positive | Positive | Negative | Negative | Positive |
In three samples, it was possible to match PAX8/PPARG expression between corresponding FNA and FFPE samples (two FA and one FTC). In one patient, in whom the FFPE sample was positive for the rearrangement, the rearrangement could not be detected in the corresponding FNA sample, and in three patients showing positive FNA results, the rearrangement could not be identified in the corresponding FFPE sample.
FNA, fine needle aspiration; FFPE, formalin-fixed paraffin-embedded.