. Author manuscript; available in PMC: 2012 Oct 2.

Published in final edited form as: Transplantation. 2011 Apr 27;91(8):858–863. doi: 10.1097/TP.0b013e31820f42d9

Table 2.

Association of trial characteristics with the outcome of trial exclusion of participants over 65 years of age in multivariable logistic regression ^a

Trial characteristic	Odds Ratio	95% C.I.	p-value
Era 1999 – 2002 2003 – 2005 2006 – 2008	Reference 0.84 0.80	Reference 0.49, 1.46 0.45, 1.43	Reference 0.54 0.45
Number of patients enrolled 0 – 52 53 – 123 ≥124	Reference 0.82 0.59	Reference 0.47, 1.42 0.32, 1.07	Reference 0.48 0.08
Location of Patient Enrollment Enrollment only in the U.S. Enrollment in the U.S. and Non-U.S. countries Enrollment only in non-U.S.	Reference 1.08 1.62	Reference 0.34, 3.39 0.82, 3.18	Reference 0.90 0.17
Immunosuppression trial (versus non-immunosuppression)	2.40	1.36, 4.22	0.01
Higher impact journal (versus lower)	1.74	1.07, 2.84	0.03

The multivariable logistic model included all trial characteristics listed in the table