TABLE 1.
mR | mL | kr | kf | Ka | R2 |
---|---|---|---|---|---|
| |||||
μm−2 | μm−2 | s−1 | ×10−4 s−1 μm−2 | ×104 μm−2 | |
CCAD (7) | CEC1245 Fc (10) | 0.31 ± 0.06 | 7.2 ± 0.9 | 30 ± 9 | 0.91 |
CCAD (7) | CEC12 Fc (155) | 0.9 ± 0.2 | 1.3 ± 0.2 | 1.4 ± 0.5 | 0.78 |
CCAD (44) | CEC1–5 W2A His6 (556) | 0.08 ± 0.01 | 0.008 ± 0.001 | 0.09 ± 0.02 | 0.91 |
CCAD W2A (24) | CEC1–5 Fc (452) | 0.10 ± 0.03 | 0.01 ± 0.002 | 0.12 ± 0.05 | 0.78 |
CCAD W2A (24) | CEC1–5 Fc (328) | 0.07 ± 0.02 | 0.008 ± 0.002 | 0.10 ± 0.05 | 0.81 |
The contact area AC was approximately 3 μm2. The numbers in parentheses are the cadherin densities in #/μm2.