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. Author manuscript; available in PMC: 2012 Oct 2.
Published in final edited form as: J Biol Chem. 2007 Nov 13;283(4):1848–1856. doi: 10.1074/jbc.M708044200

TABLE 1.

Summary of thermodynamic and kinetic constants determined from fits of Equation 2 to adhesion time courses in Figs. 4 and 6

mR mL kr kf Ka R2

μm−2 μm−2 s−1 ×10−4 s−1 μm−2 ×104 μm−2
CCAD (7) CEC1245 Fc (10) 0.31 ± 0.06 7.2 ± 0.9 30 ± 9 0.91
CCAD (7) CEC12 Fc (155) 0.9 ± 0.2 1.3 ± 0.2 1.4 ± 0.5 0.78
CCAD (44) CEC1–5 W2A His6 (556) 0.08 ± 0.01 0.008 ± 0.001 0.09 ± 0.02 0.91
CCAD W2A (24) CEC1–5 Fc (452) 0.10 ± 0.03 0.01 ± 0.002 0.12 ± 0.05 0.78
CCAD W2A (24) CEC1–5 Fc (328) 0.07 ± 0.02 0.008 ± 0.002 0.10 ± 0.05 0.81

The contact area AC was approximately 3 μm2. The numbers in parentheses are the cadherin densities in #/μm2.