Table 2.
Incidence of knee replacement/high tibial osteotomy (TKR) due to osteoarthritis in relation to leisure time physical activity
| Physical activity leisure, baseline | Cases, n | RR (95% CI)* | P, trend | RR (95% CI)† | P, trend | RR (95% CI) ‡ | P, trend |
|---|---|---|---|---|---|---|---|
|
TKR |
|
|
|
|
|
|
|
|
All |
|
|
|
|
|
|
|
| Low (n = 6934) |
104 |
1.0 |
0.398 |
1.0 |
0.898 |
1.0 |
0.087 |
| Low-moderate (n = 6949) |
122 |
1.15 (0.88, 1.49) |
|
1.13 (0.87, 1.47) |
|
1.31 (1.00, 1.70) |
|
| Moderate-high (n = 6973) |
124 |
1.16 (0.89, 1.51) |
|
1.13 (0.87, 1.46) |
|
1.36 (1.04, 1.77) |
|
| High (n = 6957) |
117 |
1.13 (0.86, 1.47) |
|
1.03 (0.79, 1.34) |
|
1.27 (0.97, 1.66) |
|
|
Men |
|
|
|
|
|
|
|
| Low (n = 2777) |
34 |
1.0 |
0.046 |
1.0 |
0.390 |
1.0 |
0.163 |
| Low-moderate (n = 2639) |
36 |
1.09 (0.68, 1.74) |
|
1.03 (0.64, 1.64) |
|
1.08 (0.68, 1.73) |
|
| Moderate-high (n = 2604) |
48 |
1.47 (0.95, 2.29) |
|
1.31 (0.84, 2.03) |
|
1.44 (0.93, 2.25) |
|
| High (n = 2925) |
51 |
1.44 (0.94, 2.22) |
|
1.15 (0.74, 1.77) |
|
1.28 (0.83, 1.99) |
|
|
Women |
|
|
|
|
|
|
|
| Low (n = 4157) |
70 |
1.0 |
0.648 |
1.0 |
0.548 |
1.0 |
0.349 |
| Low-moderate (n = 4310) |
86 |
1.17 (0.85, 1.60) |
|
1.18 (0.86, 1.62) |
|
1.42 (1.03, 1.96) |
|
| Moderate-high (n = 4369) |
76 |
1.02 (0.73, 1.41) |
|
1.03 (0.74, 1.43) |
|
1.29 (0.93, 1.79) |
|
| High (n = 4032) | 66 | 0.97 (0.69, 1.36) | 0.94 (0.67, 1.32) | 1.22 (0.87, 1.72) |
Incidence of knee replacement, or high tibial osteotomy, due to osteoarthritis during a mean follow-up of 11 years, in relation to leisure time physical activity at baseline (low (Q1), low–moderate (Q2), moderate–high (Q3), and high physical activity (Q4)).
*crude, † adjusted for age, gender, ‡ adjusted for age, gender (for all subjects only), BMI, education, smoking, marital status.