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. 2012 Oct 2;7(10):e46893. doi: 10.1371/journal.pone.0046893

Figure 3. Homeostasis model assessment of insulin resistance (HOMA-IR), insulin sensitivity as delta (Δ) in glycemia after intracerebroventricular insulin infusion (ICVII) and glycemia during an intraperitoneal insulin tolerance test (IPITT). A.

Figure 3

HOMA-IR index in rats that received saline (C) or chronic leptin (L) and pair-fed group (PF). B. Delta (Δ) in glycemia ([glycemia after 120 min of insulin bolus] – [glycemia before insulin bolus]) in rats that received saline plus acute insulin (insulin, C+I), chronic leptin plus acute insulin (L+I) and the pair-fed group plus insulin (PF+I). C. Serum glucose levels before (0 min) and during (30, 60, 90 and 120 min) an IPITT. *p<0.05, **p<0.01 by ANOVA.