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. 2012 Oct 2;7(10):e46573. doi: 10.1371/journal.pone.0046573

Table 2. Analysis of sensitivity/specificity ratio of C3256T heteroplasmy.

Actual state Area under ROC-curve Cut-off value of C3256T heteroplasmy level Sensitivity Specificity
High predisposition to atherosclerosis 0.625 (95%CI, 0.528–0.722, P = 0.012) 19.5% 63.6% 63.3%
The presence of any atherosclerotic plaque in any visualized carotid segment 0.675 (95%CI, 0.596–0.753, P<0.001) 17.5% 60.7% 63.1%
The presence of CHD 0.604 (95% CI, 0.500–0.707, P = 0.036) 19.5% 60.0% 62.3%
The history of myocardial infarction 0.726 (95%CI, 0.510–0.943, P = 0.042) 22.5% 71.4% 69%