Table 2. Analysis of sensitivity/specificity ratio of C3256T heteroplasmy.
Actual state | Area under ROC-curve | Cut-off value of C3256T heteroplasmy level | Sensitivity | Specificity |
High predisposition to atherosclerosis | 0.625 (95%CI, 0.528–0.722, P = 0.012) | 19.5% | 63.6% | 63.3% |
The presence of any atherosclerotic plaque in any visualized carotid segment | 0.675 (95%CI, 0.596–0.753, P<0.001) | 17.5% | 60.7% | 63.1% |
The presence of CHD | 0.604 (95% CI, 0.500–0.707, P = 0.036) | 19.5% | 60.0% | 62.3% |
The history of myocardial infarction | 0.726 (95%CI, 0.510–0.943, P = 0.042) | 22.5% | 71.4% | 69% |