Table 2. Regions showing ALFF differences between the pre-TIPS cirrhotic patients and healthy controls.

Brain regions	BA	MNI Coordinates (mm)	ΔVol (mm3)	Peak t value
		(x, y, z)
Left PCu	5/7	−3,−63,51	972	−2.51
Right parietal lobe (angular cortex)	40	3, −39,66	756	−2.55
Left MPFC	10	0,51,15	864	−2.61
Right ACC	32/9	9,36,21	459	−2.55
Right SMA	6	3,0,60	567	−2.52
Left DLPFC	9/46	−42,6,24	648	−2.47
Right DLPFC	9/46	45,24,27	513	−2.54
Right superior frontal cortex	8	18,36,42	891	−2.46
Right insular cortex	13/22	42,−6,−9	1080	+5.00

Positive sign in the peak t-score represents increase, and negative sign represents decrease. All P <0.05, corrected for multiple comparisons using AlphaSim program. ΔVol: volume difference; ALFF  =  amplitude of low frequency fluctuation; TIPS  =  Transjugular intrahepatic portosystemic shunt; BA  =  Brodmann's area; PCu  =  precuneus; MPFC  =  medial prefrontal cortex; ACC  =  anterior cingulate cortex; SMA  =  supplementary motor area; DLPFC  =  dorsal lateral prefrontal cortex.