Figure 4. Impact of Mini5B expression on the growth of MCF7 cell xenografts in immunodeficient mice.

(A) Mini5B–Luc, Ires–Luc, Mini5B–Luc empty shRNA, or Mini5B–Luc CYS shRNA xenografts. Tumor growth was monitored once a week for 118 days. *P<0.02, ** P<0.005. (B) Examples of tumor growth and metastasis on days 62 and 118 in anesthetized mice using the Xenogen apparatus.