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. 2001 Jun 19;98(13):7093–7100. doi: 10.1073/pnas.121146898

Figure 7.

Figure 7

Number of dendritic spines per 10 μm obtained from the apical portion of the CA1 pyramidal cell dendritic tree. Values are the mean ± SEM for different stages of the estrous cycle. Normally, spine density decreases after the progesterone surge at the time of ovulation; hence, the decrease in the 24 h between the day of proestrus and the day of estrus. The progesterone receptor antagonist, RU38486, given on proestrus, prevented the decline of spine density. **, Different from other groups, P < 0.01. [Reproduced with permission from ref. 30 (Copyright 1993, Wiley–Liss, Inc., a subsidiary of John Wiley & Sons, Inc.)].