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. 2012 Oct 2;7(10):e45688. doi: 10.1371/journal.pone.0045688

Figure 3. Pyramidal cells show gamma-synchronized activity when cells receive shunting inhibition.

Figure 3

(A) Spike histograms and simulated LFP traces for the unconnected (Inline graphic FS to P synapses per P -cell) and connected (Inline graphic FS to P synapses per P -cell) conditions. Other input to the P -cells consisted of constant-rate Poisson spike trains. (B) Amplitude spectra for the simulated LFP in the connected (red) and unconnected (blue) conditions. The LFP spectrum for the connected condition shows a clear increase in power in the gamma band (30–80 Hz). (C) Relative gamma band power (top) and pyramidal cell network synchronization (bottom) as a function of the average number of GABA -ergic projections from the FS cells to a single P -cell. Relative gamma power increases steadily with the number of synapses, reaching a maximum at Inline graphic synapses per P -cell. Network synchronization starts to occur at Inline graphic synapses per P -cell. Shown are the mean values for Inline graphic simulation runs; error bars represent Inline graphic confidence interval.