Table 7.
Studies with minimum 5-year followup comparing wear, osteolysis, and clinical function score between XLPE and conventional PE
| Study | Design | THA type | Femoral head | XLPE/PE type | Mean followup (years)* | Annual linear steady state wear (mm/year)† | Wear assessment method | Osteolysis | Function score |
|---|---|---|---|---|---|---|---|---|---|
| Capello et al. [5] (2011) | Retrospective matched control | Uncemented | CoCr 28 mm | Crossfire®/Stryker® UHMWPE | 7.5 (6–10.2) | XLPE: 0.031 (0.01) PE: 0.14 (0.08) |
Image analysis Livermore et al. [32] |
XLPE no osteolysis | NR |
| Garcia-Rey et al. [17] (2008) | Randomized | Uncemented | CoCr 28 mm | Durasul®/Sulene® | 5.5 (5–7.7) | XLPE: 0.006 (0.007‡) PE: 0.036 (0.01‡) |
Image analysis Dorr and Wan [13] |
No osteolysis | No difference |
| Fukoi et al. [16] (2011) | Consecutive series | Uncemented/hybrid | Zirconia ceramic 26 mm | Longevity®/Zimmer® UHMWPE | 5.4 (5–6.4) | XLPE: 0.0068 (NR) PE: 0.01 (NR) |
Image analysis Easy Scale for Orthopaedics v 3.1.2. (Nexis, Tokyo, Japan) |
XLPE no osteolysis | NR |
| Leung et al. [31] (2007) | Randomized | Uncemented | CoCr 28 mm | Marathon®/Enduron® | 5 | XLPE: 0.01 (NR) PE: 0.2 (NR) |
Image analysis Martell and Berdia [33] |
XLPE reduced osteolysis | NR |
| McCalden et al. [34] (2009) | Randomized | Hybrid | CoCr 28 mm | Longevity®/Zimmer® UHMWPE | 6.8 (5.6–7.6) | XLPE: 0.003 (0.05‡) PE: 0.051 (0.04‡) |
Image analysis Martell and Berdia [33] |
NR | No difference |
| Olyslaegers et al. [39] (2008) | Retrospective matched control | Hybrid | CoCr 28 mm | Longevity®/Zimmer® UHMWPE | 5 | XLPE: 0.05 (NR) PE: 0.1 (NR) |
Image analysis Martell and Berdia [33] |
No difference | No difference |
| Rayadhyaksha et al. [43] (2009) | Retrospective matched control | Uncemented/hybrid | CoCr 28 mm | Crossfire®/Stryker® UHMWPE | 6.1 (5–8.1) | XLPE: 0.054 (0.047) PE: 0.13 (0.076) |
Image analysis Martell and Berdia [33] |
NR | No difference |
| Thomas et al. [52] (2011) | Randomized | Hybrid | CoCr 28 mm | Longevity®/Zimmer® UHMWPE | NR (7–7.8) | XLPE: 0.005 (0.02‡) PE: 0.037 (0.03‡) |
RSA Selvik [50] |
No difference | No difference |
| Current study | Randomized | Cemented | CoCr 28 mm | Durasul®/Sulene® | 10 | XLPE: 0.005 (0.01) PE: 0.055 (0.05) |
RSA Selvik [50] |
No difference | No difference |
* Values are expressed as mean, with range in parentheses; †values are expressed as mean, with SD in parentheses; ‡SD was calculated by 0.5 x 95% CI x √N, where N = number of participants in group; XLPE = highly crosslinked polyethylene; PE = polyethylene; NR = not reported; RSA = radiostereometry.