Table 1.
Patient characteristics according to HFE genotype
| Characteristic | Total Patients | WT/WT | C282Y/WT | H63D/WT | H63D/H63D | C282Y/H63D |
|---|---|---|---|---|---|---|
| Number | 786 (100) | 490 (62) | 89 (11) | 177 (23) | 17 (2) | 13 (2) |
| Age (yrs) | 49.4 ± 1.4 | 48.5 ± 11.6 | 47.5 ± 11.2 | 49.4 ± 11 | 51.2 ± 12.4 | 49.5 ± 11.7 |
| Male (No.) | 281 (36) | 175 (62) | 26 (9) | 65 (23) | 8 (3) | 7 (3) |
| BMI (kg/m2) | 34.5 ± 1.1 | 34.2 ± 6.4 | 34.0 ± 5.6 | 34.5 ± 6.7 | 36.7 ± 6.9 | 35.3 ± 5.3 |
| Obese (≥30 BMI) | 574 (73) | 354 (62) | 65 (11) | 131 (23) | 14 (2) | 10 (2) |
| Diabetes mellitus | 228 (29) | 140 (61) | 26 (11) | 53 (23) | 4 (2) | 5 (2) |
| Race (No.) | ||||||
| White | 671 (85) | 392 (58) | 86 (13)† | 167 (25)† | 15 (2) | 11 (2) |
| Black | 24 (3) | 20 (83) | 2 (8) | 1 (4)† | 1 (4) | 0 (0) |
| Asian | 40 (5) | 37 (93) | 1 (3)† | 2 (5)† | 0 (0) | 0 (0) |
| American Indian or Alaska Native | 53 (7) | 34 (64) | 2 (4) | 9 (17) | 5 (9) | 3 (6) |
| Other | 38 (8) | 21 (55) | 2 (5) | 10 (26) | 4 (11) | 1 (3) |
| Ethnicity (No.) | ||||||
| Non- Hispanic | 703 (89) | 429 (61) | 87 (12) | 160 (23) | 16 (2) | 11 (2) |
| Hispanic | 83 (11) | 61 (73) | 2 (2) | 17 (21) | 1 (1) | 2 (2) |
Values are N (%) or mean ± SD
†
P < 0.05 vs WT/WT from Fisher’s exact test for categorical variables