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Immunohistochemistry with an antibody against FMRP in a rat trained on a motor skill learning task for 7 days (A); a rat maintained inactive in its cage for 7 days except for a brief daily period of handling (B); a rat exposed to a complex, social, and toy-filled environment for 20 days (C); and a rat similar to the one described in B but housed for 20 days (D). (Modified from ref. 25.)
