Table 1.
Baseline characteristics of the randomized subjects (median, 25th, and 75th percentile in parentheses)
| Treatment group | T+NES 0 mg/d | T+NES 8 mg/d | T+NES 12 mg/d | P value |
|---|---|---|---|---|
| Subjects, n | 32 | 33 | 34 | |
| Age (yr) | 27 (22, 37) | 29 (22, 34) | 23 (21, 39) | 0.61 |
| Ethnicity | 0.92 | |||
| Hispanic | 25% | 27% | 29% | |
| Non-Hispanic | 75% | 73% | 71% | |
| Race | 0.08 | |||
| White | 50% | 73% | 74% | |
| African-American | 16% | 9% | 21% | |
| Asian | 22% | 3% | 3% | |
| Others | 13% | 15% | 3% | |
| Weight (kg) | 78.2 (76.4, 83.6) | 75.4 (70.0, 82.7) | 80.0 (74.6, 88.6) | |
| BMI (kg/m2) | 25.0 (23.5, 26.8 | 24.8 (22.3, 26.7) | 25.4 (24.1, 26.7) | 0.68 |
| Height (cm) | 154 (147, 158) | 152 (147, 156) | 156 (150, 161) | 0.13 |
| Serum hormone levels | ||||
| Total T (nmol/liter) | 21.1 (17.1, 25.7) | 20.2 (15.1, 23.7) | 20.1 (15.8, 24.2) | 0.66 |
| LH (IU/liter) | 3.4 (2.8, 5.0) | 3.2 (2.5, 4.7) | 3.5 (2.2, 4.3) | 0.41 |
| FSH (IU/liter) | 3.2 (2.1, 4.7) | 3.1 (2.1, 4.5) | 3.5 (2.2, 4.3) | 0.93 |
| Sperm concentration (106/ml) | 53.4 (34.8, 74.1) | 50.4 (33.3, 74.0) | 48.2 (29.3, 64.4) | 0.57 |
| Total sperm per ejaculate (×106) | 172 (126, 263) | 134 (83, 186) | 129 (62, 193) | 0.05 |
| Testicular size (both sides in milliliter) | 50 (44, 53) | 50 (42, 52) | 50 (46, 50) | 0.82 |
BMI, Body mass index.