Fig. 4.

Baseline and LDC-stimulated cortisol (left two panels) and DHEA (right two panels) serum levels in 18 patients with central AI (IMPAIRED-HPA) who achieved an LDC- stimulated cortisol concentration of greater than 18.0 μg/dl are shown here. Although the cortisol responses may suggest an adequate cortisol response to LDC, DHEA levels are very low at baseline with a much blunted response to LDC. All 18 subjects are confirmed to have significantly reduced DHEA levels when compared with age- and gender-appropriate levels.