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. 2012 Oct;64(4):939–971. doi: 10.1124/pr.112.006163

Fig. 11.

Fig. 11.

Pathophysiological pain conditions in which central sensitization has been implicated. Central sensitization is believed to be a key phenomenon contributing to the development of a number of these chronic pain conditions. Increased knowledge of CS may therefore lead to the development of new compounds, which can help improve the outcome of such conditions.