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. 2012 Oct 2;12(1):290–303. doi: 10.1102/1470-7330.2012.0034

Table 1.

TNM staging of colorectal cancer (based on American Joint Committee on Cancer Cancer Staging Manual, 7th edition)

Stage Finding
Tumour
    Tx Primary tumour cannot be assessed
    T0 No evidence of primary tumour
    T1 Tumour invades submucosa
    T2 Tumour invades muscularis propria
    T3 Tumour invades through muscularis propria into perirectal tissues
    T4a Tumour penetrates to surface of visceral peritoneum
    T4b Tumour directly invades or is adherent to other organs or structures
Regional nodal metastases
    Nx Regional nodes cannot be assessed
    N0 No regional node metastases
    N1 Metastases in 1–3 regional nodes
    N2 Metastases in 4 or more regional nodes
Distant metastases
    M0 No distant metastases
    M1a Distant metastases confined to one organ/site
    M1b Metastases in more than one organ/site or peritoneum