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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Bioorg Med Chem Lett. 2012 Aug 10;22(19):6229–6232. doi: 10.1016/j.bmcl.2012.08.012

Table 2.

Structures and activities of compounds 8 – 17.

graphic file with name nihms403161t1.jpg
R- IC50 for IMP-1 IC50 for Bla2
8 4-Cl-phenyl >200 >200
9 4-Br-phenyl >200 >200
10 3-NH2-phenyl 77.0 4.9
11 3-acetamido-phenyl >200 >200
12 3-BOCNH-phenyl >200 74.1
13 2-OH-phenyl >200 >200
14 graphic file with name nihms403161t2.jpg >200 >200
15 graphic file with name nihms403161t3.jpg >200 >200
16 graphic file with name nihms403161t4.jpg >200 >200
17 graphic file with name nihms403161t5.jpg >200 >200