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. 2012 Jul 19;7(10):1632–1638. doi: 10.2215/CJN.02730312

Table 3.

Rates of secondary outcomes (per 1000 dialysis sessions) for standard and buttonhole needling

Outcomes Standard Needling Rate per 1000 Dialysis Sessions Buttonhole Needling Rate per 1000 Dialysis Sessions P Value
Hematoma formation 436 295 0.003
Bleeding postdialysis
 No bleeding 23.6 28.3
 Any bleeding 97.6 97.2 0.40
Signs of localized infection 22.4 50.0 0.003

Signs of localized infection included erythema, pus, or swelling at the fistula site.