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. 2012 Aug 2;7(10):1646–1653. doi: 10.2215/CJN.04570512

Table 3.

Relation of an interleg difference in SBP of ≥15 mmHg or DBP of ≥10 mmHg to overall and cardiovascular mortality using the Cox proportional hazards model

Interleg BP Difference Overall Mortality Cardiovascular Mortality
HR (95% CI) P HR (95% CI) P
Unadjusted 3.94 (2.11–7.35) <0.01 5.73 (2.40–13.68) <0.01
Age and sex adjusted 3.30 (1.76–6.18) <0.01 4.71 (1.96–11.30) <0.01
Multivariate adjusted model 1 3.09 (1.62–5.91) <0.01 4.92 (1.98–12.24) <0.01
Multivariate adjusted model 2 3.36 (1.68–6.72) <0.01 4.84 (1.84–12.71) <0.01
Multivariate adjusted model 3 2.91 (1.28–6.64) 0.01 3.15 (1.05–9.44) 0.04

Multivariate model 1 is adjusted for age, sex, diabetes mellitus, hypertension, coronary artery disease, and cerebrovascular disease. Multivariate model 2 comprises model 1 as well as mean arterial pressure, pulse pressure, albumin, log triglyceride, total cholesterol, hemoglobin, creatinine, phosphorous, calcium-phosphorous product, and log high-sensitivity CRP. Multivariate model 3 comprises model 2 as well as ABI <0.9 and brachial-ankle PWV. HR, hazard ratio; CI, confidence interval; SBP, systolic BP; DBP, diastolic BP; ABI, ankle-brachial index; PWV, pulse wave velocity; CRP, C-reactive protein.