Fig. 4.

The transactivation of Aldh1a1 promoter activity by Jun family proteins. HepG2 cells were transiently cotransfected with the p2.0Aldh1a1Luc construct with increasing concentrations (0, 20, 40, and 80 ng) of either c-Jun, JunD, or JunB expression plasmid. Luciferase activities from at least three independent experiments are expressed as fold induction ± S.D. compared with that for vector-transfected cells. *, p < 0.05, significantly different compared with vector-transfected cells (one-way ANOVA followed by the Tukey test).