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Expression of Migfilin in normal brain tissue and glioma tissue (×400). A, normal brain cells exhibit no immunoreactivity for Migfilin. B, high levels of Migfilin were detected in blood vessel endothelial cells. C and D, Migfilin exhibits weak immunoreactivity in grade I and grade II gliomas. E, Migfilin exhibits moderate immunoreactivity in grade III glioma. F, Migfilin exhibits strong immunoreactivity in grade IV glioma.
