TABLE 1.

Pathway analysis of carbonylated mitochondrial proteins in adipocytes

Proteins underlined are pathway-specific targets of carbonylation, whereas others are represented in two or more pathways.

Pathway	Pathway coverage	Carbonylated proteins
Tricarboxylic acid cycle	19/58	ACO2, CS, DLD, DLST, FH, IDH1, IDH2, IDH3A, IDH3G, MDH1, MDH2, OGDH, PC, PCK2, SDHA, SDHB, SUCLA2, SUCLG1, SUCLG2
Oxidative phosphorylation	32/165	ATP5A1, ATP5B, ATP5C1, ATP5F1, ATP5H, ATP5I, ATP5O, ATP6V1A, COX15, COX4I1, COX5A, COX5B, CYC1, MT-ATP8, MT-CO2, NDUFA2, NDUFA3, NDUFA4, NDUFA10, NDUFB4, NDUFB5, NDUFC2, NDUFS1, NDUFS3, NDUFS7, PPA2, SDHA, SDHB, UQCRB, UQCRC1, UQCRC2, UQCRFS1
Branched chain amino acid catabolism	31/111	ACAD9, ACAD10, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACAT1, ALDH2, ALDH1B1, ALDH4A1, ALDH6A1, BCAT2, BCKDHA, DBT, ECH1, ECHS1, HADH, HADHA, HADHB, HIBCH, HMGCL, HSD17B4, HSD17B10, IVD, MCCC1, MCCC2, MUT, OXCT1, PCCA, PCC