TABLE 2.

Differentially modified targets of carbonylation in adipocyte mitochondria

Values represented as -fold change with positive numbers indicate elevated carbonylation and negative numbers designating decreased carbonylation relative to the compared cell type. Data in the GSTA4 Kd versus aP2-HA-GSTA4 column have been normalized to respective controls. p values are calculated with ratio data from three or more matched spectra.

Accession number	Protein symbol	Protein name	GSTA4 Kd vs. Scr		aP2-HAGSTA4 vs. pcDNA		GSTA4 Kd vs. aP2-HAGSTA4
			-Fold	p value	Fold	p value	Fold	p value
Q8VEM8	MPCP	Phosphate carrier protein, mitochondrial	2.59	2.5E − 06	−2.06	6.9E − 05	5.33	<E − 15
Q9CQ91	NDUFA3	NADH dehydrogenase (ubiquinone) 1α subunit 3	1.62	2.9E − 01	−2.95	2.8E − 06	4.77	3.3E − 06
Q9D880	TIM50	Mitochondrial import inner membrane translocase subunit TIM50	1.06	8.8E − 01	−2.40	1.7E − 03	2.56	4.0E − 02
Q9CQ75	NDUFA2	NADH dehydrogenase (ubiquinone) 1α subunit 2	−1.02	9.4E − 01	−2.21	2.0E − 13	2.17	9.3E − 06
Q3U2A8	SYVM	Valyl-tRNA synthetase, mitochondrial	1.02	9.3E − 01	−1.82	1.6E − 10	1.85	4.7E − 02
Q9DCU6	RM04	39 S ribosomal protein L4, mitochondrial	−1.68	2.1E − 04	−1.24	2.3E − 02	−1.35	2.0E − 04
P84091	AP2M1	Adaptor-related protein complex 2, μ1 subunit	−2.52	8.0E − 15	1.00	9.9E − 01	−2.51	1.7E − 05
P22315	HEMH	Ferrochelatase, mitochondrial	−2.23	2.4E − 09	1.32	5.1E − 01	−2.95	4.0E − 02
Q8JZN7	MIRO2	Mitochondrial Rho GTPase 2	−2.66	3.0E − 13	1.22	3.5E − 01	−3.23	9.8E − 15
Q8R127	SCPDH	Saccharopine dehydrogenase (putative)	−2.36	1.3E − 11	1.52	1.6E − 01	−3.58	1.1E − 10