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. 2012 Jul 18;287(39):33061–33069. doi: 10.1074/jbc.M111.307348

FIGURE 3.

FIGURE 3.

Short term overfeeding impairs the ability of MBH insulin to suppress hepatic GP. A, glucose infusion rate (GIR) required to maintain euglycemia (n ≥ 5/group). B, area under the curve (AUC) of graph in A (n ≥ 5/group). C, GP at base line and during the 1 milliunit·kg−1·min−1 clamp period (n ≥ 4/group). D, GP suppression (n ≥ 4/group). E, glucose disposal during the clamp period (n ≥ 4/group). All error bars represent S.E. *, p < 0.05; **, p < 0.01; and ***, p < 0.001 versus RC MBH vehicle + 1 milliunit·kg−1·min−1 clamp group unless otherwise indicated. #, p < 0.05; ##, p < 0.01; and ###, p < 0.001 versus HFD groups.